CEPHALEXIN MONOHYDRATE
CEPHALEXIN MONOHYDRATE
CAS: 23325-78-2
Molecular Formula: C16H19N3O5S
CEPHALEXIN MONOHYDRATE - Names and Identifiers
| Name | CEPHALEXIN MONOHYDRATE |
| Synonyms | 23325-78-2 CEFALEXIN HYDRATE CEPHALEXIN HYDRATE CEPHALEXIN MONOHYDRATE |
| CAS | 23325-78-2 |
| EINECS | 629-748-1 |
CEPHALEXIN MONOHYDRATE - Physico-chemical Properties
| Molecular Formula | C16H19N3O5S |
| Molar Mass | 365.4 |
| Boling Point | 727.4℃ at 760 mmHg |
| Water Solubility | 13.5g/L(25 ºC) |
| Appearance | White crystalline solid with bitter taste |
| Storage Condition | 2-8℃ |
| Refractive Index | 154 |
| Physical and Chemical Properties | Bioactive cephalexin monohydrate is an effective, orally administered first-generation cephalosporin antibiotic. Cephalexin chemical knohydrate kills gram-positive and some Gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate was used in studies Pneumonia, strep throat, bacterial endocarditis, etc. |
| Use | Use antibiotics and antiviral |
CEPHALEXIN MONOHYDRATE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 42/43 - May cause sensitization by inhalation and skin contact. |
| Safety Description | S22 - Do not breathe dust. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24/25 - Avoid contact with skin and eyes. |
CEPHALEXIN MONOHYDRATE - Voltammetric behavior of degradation products of cephalexin on silver microdisk electrode and its application
from VIP
Author:
Abstract:
Based on the characteristic that the degradation products of cefalexin contain sulfhydryl group and can form insoluble compounds with Ag ^ +, the voltammetric behavior of CEX degradation products was studied on a silver microdisk electrode, the mechanism of electrode reaction was discussed. Using Differential pulse Stripping Voltammetry in 0.1mol/L HAc-NaAc medium, the reduction peak current of CEX degradation products was linear with the concentration of CEX in the range of 8.0 × 10 ^-8-7.0 × 10 ^-6mol/L; the detection limit was 1.0 × 10 ^ 08mol/L. The content of CEX was 92.0% Cefalexin Capsules.
Key words:
cephalexin degradation products Cathodic stripping voltammetry electrochemical analysis
DOI:
10.1007/BF02009548
cited:
year:
1997
Last Update：2024-01-02 23:10:35
CEPHALEXIN MONOHYDRATE - Study on the determination of cefalexin by photochemical fluorimetry
from VIP Journal Professional Edition
Author:
Abstract:
in a pH 4.0 buffer solution, cephalexin undergoes a photochemical reaction under UV light to form a fluorescent product, 345nm for lambda ex and 432nm for lambda em. There was a good linear relationship between the fluorescence intensity and the Cefalexin concentration in the range of 0.1-4.0 μg/ml. The detection limit was 0.01 μg/ml and the relative standard deviation was 0.93%. The method is simple, rapid and sensitive, and can be used for the determination of cefalexin in urine.
Key words:
cephalexin photochemical analysis fluorescence analysis
DOI:
CNKI:SUN:FXHX.0.1994-12-004
cited:
year:
1994
Last Update：2023-08-16 22:05:47
CEPHALEXIN MONOHYDRATE - Preparation Method of cefalexin
from Palm Bridge research
Application (patent) number:
CN93115244.5
application date:
1993-12-02
Public/Announcement Number:
CN1103403A
Public/announcement date:
1995.06.07
applicant (patent):
Shandong Xinhua Pharmaceutical Factory
inventor:
National and provincial code:
CN370303
cited:
Abstract:
A process for the preparation of cephalexin (I), wherein the compound (III) is prepared by silanating 7-aminodeacetoxycephalosporin acid with chlorotrimethylsilane in the presence of tertiary amine, the compound (II) is prepared by using phenylglycine tannins and chloroformic acid esters under the catalysis of organic base, and the compound (I) is prepared by acylation and hydrolysis of (III) and (II). Conversion rate of acylation reaction can be controlled at more than or equal to 97%, the one-time crystallization rate of cephalexin is 75 ~ 78%, and the yield of finished product is 85 ~ 88%, which is significantly higher than that of 2, 2-dimethylpropionyl chloride process, the price of chloroformic acid esters is only 28.89% of the original process, the cost is greatly reduced, and it is more suitable for industrialization.
Last Update：2023-08-16 22:05:47
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Tel: 0714-3999186
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Mobile: 86+15671228036
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Product Name: CEPHALEXIN MONOHYDRATE Request for quotation
CAS: 23325-78-2
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Mobile: 0086 189 4982 3763
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Product List: View Catalog
CAS: 23325-78-2
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Multiple Specifications
Product Name: Cephalexin Monohydrate Visit Supplier Webpage Request for quotationCAS: 23325-78-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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